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Arkansas vs. Memphis Prediction, Betting Odds & How To Watch

Colton Pool by Colton Pool
September 19, 2025
Memphis head coach Ryan Silverfield

AP Photo/George Walker IV

Memphis has done nothing but win decisively over every opponent the Tigers have faced. 

They are 3-0 with all of their wins being decided by at least 20 points. They beat Chattanooga 45-10, then went on the road to defeat Georgia State 38-16 and Troy 28-7.

But now they will take on their best opponent yet before they begin American Conference play. Memphis, the No. 3 team in this week’s HERO Sports Group of Five Top 25 media poll, will face Arkansas at home.


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Arkansas vs. Memphis College Football Betting

Arkansas is a -7 college football betting odds favorite against Memphis, with the Over/Under being 60.5. 

The moneyline for Arkansas is -275, while it’s +220 for Memphis.


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Arkansas vs. Memphis On TV

The matchup between Arkansas and Memphis will be televised on ABC. 

The game will kick off at noon ET on Saturday, Sept. 20. The contest is taking place at Simmons Bank Liberty Stadium in Memphis, Tennessee.

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Arkansas vs. Memphis Prediction

I predict Memphis is going to win and cover the seven-point spread. I also project the game is going to go Over 60.5 total points.

Arkansas could end up being a tougher test than some people would’ve expected going into the season. The Razorbacks are 2-1 with their one loss being a 41-35 decision at Ole Miss. Granted, their two wins were against Alabama A&M and Arkansas State.

But I still think Memphis is capable of pulling off an upset, especially at home. The Tigers know what’s at stake in this matchup. If they win, they would be 4-0 before their American Conference slate with a Power Four win. That P4 win would certainly bolster their case for the College Football Playoff.

And with teams like Tulane and USF, which also have P4 wins, in the same conference as well as other G5 teams which have played well thus far, the Tigers need to keep up.

At the very least, Memphis will want to keep this close, and I expect this game to be settled by less than a touchdown.

But I also think this clash will be an offensive shootout. Memphis quarterback Brendon Lewis has thrown for 608 yards, two touchdowns, and one interception while rushing for 190 yards and two TDs. But I think he’s getting more comfortable with the Tigers’ offense after transferring from Nevada and that he could have his best game yet in a Memphis uniform.

The Razorbacks’ offense has also looked pretty solid, so I think plenty of points will be scored. But at home, I’m anticipating Memphis’ defense will do just enough to set the Tigers up for a win.

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