Some talented football players have come out of Group of Five programs, and Middle Tennessee is no exception.
Here’s a look at NFL Draft picks out of Middle Tennessee.
NFL Draft Picks From Middle Tennessee
| Yr | Rd | Team | Player | Position |
| 2018 | 7 | SFO | Richie James | WR |
| 2016 | 3 | TEN | Kevin Byard | S |
| 2014 | 5 | SEA | Jimmy Staten | DT |
| 2011 | 5 | JAX | Rod Issac | DB |
| 2010 | 7 | MIA | Chris McCoy | DE |
| 2008 | 6 | DAL | Erik Walden | DE |
| 2003 | 2 | TEN | Tyrone Calico | WR |
| 2002 | 7 | JAX | Kendall Newson | WR |
| 1999 | 7 | CHI | Sulecio Sanford | WR |
| 1998 | 3 | JAX | Jonathan Quinn | QB |
| 1993 | 3 | CLE | Mike Caldwell | LB |
| 1993 | 5 | SDG | Walter Dunson | WR |
| 1992 | 6 | CIN | Chris Burns | DT |
| 1992 | 6 | RAM | Joe Campbell | RB |
| 1991 | 8 | TAM | Marty Carter | DB |
| 1987 | 12 | SEA | Tony Burse | RB |
| 1986 | 6 | SFO | Don Griffin | DB |
| 1983 | 7 | CIN | James Griffin | DB |
| 1978 | 12 | MIA | Mike Moore | RB |
| 1976 | 8 | BUF | Bobby Joe Easter | RB |
| 1976 | 14 | BUF | Tony Williams | WR |
| 1975 | 17 | MIA | Dwaine Copeland | RB |
| 1973 | 8 | BAL | Ray Oldham | DB |
| 1973 | 10 | DET | Ray Bonner | DB |
| 1968 | 10 | DEN | Bob Langford | T |
