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Eastern Michigan vs. Kentucky Prediction, Betting Odds & How To Watch

Colton Pool by Colton Pool
September 12, 2025
Eastern Michigan head coach Chris Creighton

AP Photo/Abbie Parr

Eastern Michigan hasn’t enjoyed a great start to the season.

The Eagles are 0-2 overall. They first lost at Texas State 52-27 to open the season. Not a bad loss considering Texas State is considered to be one of the top teams in the Sun Belt. 

Then EMU lost its home opener to FCS Long Island 28-23. And things likely won’t be easier for the Eagles this week.

EMU is facing Kentucky on the road. The Wildcats are 1-1 after beating another MAC team, Toledo, by just eight points and then losing to Ole Miss 30-23.

Eastern Michigan vs. Kentucky Betting Odds

Kentucky is a -25.5 college football betting odds favorite against Eastern Michigan, with the Over/Under being 48.5.

The moneyline for Eastern Michigan is +1300, while it’s -3000 for Kentucky.


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Eastern Michigan vs. Kentucky On TV

The matchup between Eastern Michigan and Kentucky will be televised on ESPNU.

The game will kick off at 7:30 p.m. ET on Saturday, Sept. 13. The contest is taking place at Kroger Field in Lexington, Kentucky.

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Eastern Michigan vs. Kentucky Prediction

I predict Kentucky will win and cover the 25.5-point spread. I also project the game will go Over 48.5 total points.

Yes, Toledo was competitive with this Kentucky squad just a few weeks ago. The Rockets lost by just one possession.

So could another MAC squad keep it close against the Wildcats? I don’t think so.

Eastern Michigan isn’t the same team that Toledo is. The Eagles just lost to an FCS team at home.

And now they have to compete with an SEC program that just lost to Ole Miss by a single touchdown.

I think Kentucky is going to be motivated to respond after a loss like that and that the Wildcats will be aggressive on offense early. If they do put up a good number of points before intermission, I don’t think EMU will be able to keep up.

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