Some talented football players have come out of Group of Five programs, and Buffalo is no exception.
Here’s a look at NFL Draft picks out of Buffalo during the Super Bowl era, which began in 1966.
NFL Draft Picks From Buffalo
| Yr | Rd | Team | Player | Position |
| 2021 | 3 | LVR | Malcolm Koonce | DE |
| 2017 | 7 | CIN | Mason Schreck | TE |
| 2015 | 6 | SEA | Kristjan Sokoli | DT |
| 2014 | 1 | OAK | Khalil Mack | LB |
| 2013 | 5 | TAM | Steven Means | DE |
| 2011 | 5 | DAL | Josh Thomas | DB |
| 2010 | 6 | GNB | James Starks | RB |
| 2008 | 6 | OAK | Trevor Scott | DE |
| 2008 | 7 | IND | Jamey Richard | T |
| 2000 | 7 | BUF | Drew Haddad | WR |
| 1997 | 4 | NWE | Ed Ellis | T |
