Some talented football players have come out of Group of Five programs, and USF is no exception.
Here’s a look at NFL Draft picks out of USF.
NFL Draft Picks From USF
| Yr | Rd | Team | Player | Position |
| 2018 | 3 | ATL | Deadrin Senat | DT |
| 2018 | 5 | GNB | Marquez Valdes-Scantling | WR |
| 2017 | 4 | IND | Marlon Mack | RB |
| 2017 | 5 | MIN | Rodney Adams | WR |
| 2017 | 6 | GNB | Kofi Amichia | C |
| 2015 | 6 | HOU | Reshard Cliett | OLB |
| 2015 | 7 | WAS | Austin Reiter | C |
| 2014 | 5 | SFO | Aaron Lynch | DE |
| 2013 | 3 | DEN | Kayvon Webster | DB |
| 2013 | 7 | GNB | Sam Barrington | LB |
| 2013 | 7 | SFO | B.J. Daniels | QB |
| 2011 | 3 | CAR | Terrell McClain | DT |
| 2011 | 6 | MIN | Mistral Raymond | DB |
| 2011 | 6 | NYG | Jacquian Williams | LB |
| 2010 | 1 | NYG | Jason Pierre-Paul | DE |
| 2010 | 2 | PHI | Nate Allen | DB |
| 2010 | 3 | STL | Jerome Murphy | DB |
| 2010 | 6 | CLE | Carlton Mitchell | WR |
| 2010 | 7 | STL | George Selvie | DE |
| 2009 | 3 | NWE | Tyrone McKenzie | LB |
| Year | Rnd | Tm | Player | Pos |
| 2008 | 1 | DAL | Mike Jenkins | DB |
| 2008 | 5 | JAX | Trae Williams | DB |
| 2007 | 4 | ATL | Stephen Nicholas | LB |
| 2004 | 4 | PHI | J.R. Reed | DB |
| 2003 | 2 | KAN | Kawika Mitchell | LB |
| 2003 | 4 | OAK | Shurron Pierson | DE |
| 2003 | 7 | GNB | DeAndrew Rubin | WR |
| 2001 | 4 | NWE | Kenyatta Jones | T |
| 2001 | 4 | CLE | Anthony Henry | DB |
| 2001 | 4 | ARI | Bill Gramatica | K |
