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UTSA vs. Colorado State Prediction, Betting Odds & How To Watch

Colton Pool by Colton Pool
September 19, 2025
UTSA quarterback Owen McCown

AP Photo/Eric Gay

Neither UTSA nor Colorado State started the season the way they wanted to. But they’ve both won their most recent games and hope to sustain that momentum in this clash.

The Roadrunners are 1-2 after losing to two in-state opponents. They fell on the road at Texas A&M 42-24. Then they were just short in a 43-36 loss against Texas State. But they did respond by taking care of business and beating FCS Incarnate Word 48-20.

But could the Roadrunners, who are ranked 20th in this week’s HERO Sports Group of Five Top 25 media poll, win back-to-back games? 

Colorado State is 1-1 but was expected to be one of the best teams in the Mountain West going into the year. The Rams lost to Washington 38-21 but got back to .500 after a narrow 21-17 victory over Northern Colorado.

UTSA vs. Colorado State College Football Betting

UTSA is a -4.5 college football betting odds favorite against Colorado State, with the Over/Under being 59.5. 

The moneyline for UTSA is -200, while it’s +165 for Colorado State.


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UTSA vs. Colorado State On TV

The matchup between UTSA and Colorado State will be televised on FS1. 

The game will kick off at 9:30 p.m. ET on Saturday, Sept. 20. The contest is taking place at Canvas Stadium in Fort Collins, Colorado.

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UTSA vs. Colorado State Prediction

I predict UTSA will win and cover the 4.5-point spread. I also project the game will go Over 59.5 total points.

I know that UTSA has a losing record at this point, but the Roadrunners will want to get back on track before beginning American Conference play if they still want to win a league title. And this would be a good game to do that.

Also, the Roadrunners haven’t been bad in their losses. They went on the road and lost to ranked Texas A&M by less than 20 points, and then fell to Texas State, which should be one of the top programs in the Sun Belt, by just a touchdown before defeating Incarnate Word.

I like UTSA’s offense, and I think that unit will shine against Colorado State. Roadrunners quarterback Owen McCown has thrown for 583 yards, six touchdowns, and no interceptions on a 65% completion rate. Robert Henry Jr. has led the way on the ground, averaging just over 10 yards per carry. He has 480 yards and six touchdowns rushing and has also caught nine passes for 20 yards and another score.

Now, led by quarterback Brayden Fowler-Nicolosi, I also like Colorado State’s offense. So I think this will be a high-scoring contest. 

But I believe UTSA’s offense is just a bit better, even on the road.

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