Caleb Williams joins five other USC Trojans to have the honor of being named the first overall pick in the draft.
Ron Yary was the first Trojan to hear his name called first on draft day back in 1968, and O.J. Simpson gave USC a repeat the year after.
Since then four other Trojans have been the first pick — Ricky Bell in 1977, Keyshawn Johnson in 1996, Carson Palmer in 2003, and Caleb Williams in 2024.
No. 1 Overall NFL Draft Picks from USC
| Year | Player | Pos. | Team |
| 1968 | Ron Yary (HOF) | T | Minnesota |
| 1969 | O.J. Simpson (HOF) | RB | Buffalo |
| 1977 | Ricky Bell | RB | Tampa Bay |
| 1996 | Keyshawn Johnson | WR | N.Y. Jets |
| 2003 | Carson Palmer | QB | Cincinnati |
| 2024 | Caleb Williams | QB | Chicago |
