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Week 4 College Football Betting Odds

HERO Sports by HERO Sports
September 21, 2021
Oklahoma football

Photo by RaksyBH/Shutterstock

Week 4 of the 2021 college football season is here. Get in on the action with online betting at BetMGM, the best sportsbook for college football betting odds.

Below are BetMGM’s Week 4 betting odds.

As of Sept. 21

ACC

Wake Forest at Virginia
Spread: Virginia -4
Total Points: 68.5

Liberty at Syracuse
Spread: Liberty -6
Total Points: 53.5

Missouri at Boston College
Spread: Missouri -2.5
Total Points: 59

Clemson at North Carolina State
Spread: Clemson -10
Total Points: 46.5

Louisville at Florida State
Spread: Louisville -2.5
Total Points: 62.5

Kansas at Duke
Spread: Duke -16
Total Points: 57.5

North Carolina at Georgia Tech
Spread: UNC -12.5
Total Points: 63.5

New Hampshire at Pitt
TBA

Richmond at Virginia Tech
TBA

CCSU at Miami (FL)
TBA

Big 12

SMU at TCU
Spread: TCU -10
Total Points: 64

Texas Tech at Texas
Spread: Texas -7.5
Total Points: 60.5

Iowa State at Baylor
Spread: Iowa State -7.5
Total Points: 47.5

Kansas at Duke
Spread: Duke -16
Total Points: 57.5

Kansas State at Oklahoma State
Spread: Oklahoma State -6
Total Points: 46

West Virginia at Oklahoma
Spread: Oklahoma -16.5
Total Points: 57.5

Big Ten

Bowling Green at Minnesota
Spread: Minnesota -31
Total Points: 51.5

Notre Dame vs. Wisconsin
Spread: Wisconsin -5.5
Total Points: 46.5

Ohio at Northwestern
Spread: Northwestern -15
Total Points: 47.5

Colorado State at Iowa
Spread: Iowa -22.5
Total Points: 44.5

Illinois at Purdue
Spread: Purdue -11
Total Points: 53

Kent State at Maryland
Spread: Maryland -14.5
Total Points: 67.5

Rutgers at Michigan
Spread: Michigan -18.5
Total Points: 51.5

Nebraska at Michigan State
Spread: Michigan State -5
Total Points: 51.5

Akron at Ohio State
Spread: Ohio State -48
Total Points: 67.5

Indiana at Western Kentucky
Spread: Indiana -9
Total Points: 62.5

Villanova at Penn State
TBA

Pac-12

Washington State at Utah
Spread: Utah -14.5
Total Points: 54.5

UCLA at Stanford
Spread: UCLA -5.5
Total Points: 58.5

California at Washington
Spread: Washington -7.5
Total Points: 46.5

Arizona at Oregon
Spread: Oregon -28.5
Total Points: 58.5

Colorado at Arizona State
Spread: Arizona State -14
Total Points: 44.5

Oregon State at USC
Spread: USC -12.5
Total Points: 63

SEC

Missouri at Boston College
Spread: Missouri -2.5
Total Points: 59

Georgia at Vanderbilt
Spread: Georgia -34.5
Total Points: 51.5

LSU at Mississippi State
Spread: LSU -2.5
Total Points: 55.5

Texas A&M vs. Arkansas
Spread: Texas A&M -5.5
Total Points: 47.5

Georgia State at Auburn
Spread: Auburn -27.5
Total Points: 56.5

Kentucky at South Carolina
Spread: Kentucky -5.5
Total Points: 49

Tennessee at Florida
Spread: Florida -20.5
Total Points: 63.5

Southern Miss at Alabama
Spread: Alabama -44.5
Total Points: 58.5

Place College Football Wagers at BetMGM

At BetMGM, you can bet on college football odds throughout the season. Whether you’re betting from your computer with online sports betting or your phone with mobile sports betting, you have access to college football betting lines all year with the King of Sportsbooks.

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