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Week 5 College Football Betting Odds

HERO Sports by HERO Sports
September 28, 2021
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Colorado football stadium

Photo by R Kristoffersen/Shutterstock

Week 5 of the 2021 college football season is here. Get in on the action with online betting at BetMGM, the best sportsbook for college football betting odds.

Below are BetMGM’s Week 5 betting odds for Power 5 conferences.

As of Sept. 28

ACC

Virginia at Miami (FL)
Spread: Miami -4
Total Points: 62

Duke at North Carolina
Spread: North Carolina -18
Total Points: 70.5

Pitt at Georgia Tech
Spread: Pitt -3.5
Total Points: 58.5

Louisville at Wake Forest
Spread: Wake Forest -7
Total Points: 61.5

Syracuse at Florida State
Spread: Florida State -4.5
Total Points: 51.5

Louisiana Tech at NC State
Spread: NC State -19.5
Total Points: 54.5

Boston College at Clemson
Spread: Clemson -16
Total Points: 46.5

Big 12

Texas at TCU
Spread: Texas -5
Total Points: 66

Oklahoma at Kansas State
Spread: Oklahoma -10.5
Total Points: 52.5

Texas Tech at West Virginia
Spread: West Virginia -7
Total Points: 56.5

Baylor at Oklahoma State
Spread: Oklahoma State -3.5
Total Points: 48

Kansas at Iowa State
Spread: Iowa State -34.5
Total Points: 58.5

Big Ten

Iowa at Maryland
Spread: Iowa -4
Total Points: 46.5

Charlotte at Illinois
Spread: Illinois -11
Total Points: 55.5

Michigan at Wisconsin
Spread: Wisconsin -1.5
Total Points: 43.5

Minnesota at Purdue
Spread: Purdue -2.5
Total Points: 47.5

Ohio State at Rutgers
Spread: Ohio State -15.5
Total Points: 56.5

Western Kentucky at Michigan State
Spread: Michigan State -11
Total Points: 61.5

Indiana at Penn State
Spread: Penn State -10.5
Total Points: 52.5

Northwestern at Nebraska
Spread: Nebraska -10.5
Total Points: 50

Pac-12

USC at Colorado
Spread: USC -7
Total Points: 51.5

Oregon at Stanford
Spread: Oregon -8.5
Total Points: 58

Washington State at California
Spread: Cal -7.5
Total Points: 52

Washington at Oregon State
Spread: Oregon State -2.5
Total Points: 56

Arizona State at UCLA
Spread: UCLA -3.5
Total Points: 55.5

SEC

Arkansas at Georgia
Spread: Georgia -18.5
Total Points: 48.5

Tennessee at Missouri
Spread: Missouri -3
Total Points: 65

Troy at South Carolina
Spread: South Carolina -7
Total Points: 44

Ole Miss at Alabama
Spread: Alabama -14.5
Total Points: 79

Florida at Kentucky
Spread: Florida -8.5
Total Points: 55.5

Mississippi State at Texas A&M
Spread: Texas A&M -7
Total Points: 47

UConn at Vanderbilt
Spread: Vanderbilt -14.5
Total Points: 52

Auburn at LSU
Spread: LSU -3.5
Total Points: 54.5

Place College Football Wagers at BetMGM

At BetMGM, you can bet on college football odds throughout the season. Whether you’re betting from your computer with online sports betting or your phone with mobile sports betting, you have access to college football betting lines all year with the King of Sportsbooks.

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