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Iowa State vs. Arkansas State Prediction, Betting Odds & How To Watch

Colton Pool by Colton Pool
September 12, 2025
Arkansas State receiver Corey Rucker

AP Photo/Michael Woods

Arkansas State is hoping to be competitive in a tough Sun Belt Conference this year. But the Red Wolves don’t have that easy of a non-conference slate, either.

Arkansas State did begin the year with a 42-24 win over Southeast Missouri, but then the Red Wolves went on the road and lost at Arkansas, 56-14.

Now Arkansas State has to take on another Power Four opponent. This time it’s at home for the Red Wolves, but it’s arguably a tougher team. They will face Iowa State, which is ranked No. 14 in the country.

Iowa State vs. Arkansas State Betting Odds

Arkansas State is a +21 college football betting odds underdog against Iowa State, with the Over/Under being 55.5.

The moneyline for Iowa State is -1600, while it’s +875 for Arkansas State.


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Iowa State vs. Arkansas State On TV

The matchup between Iowa State and Arkansas State will be televised on ESPN2.

The game will kick off at 4 p.m. ET on Saturday, Sept. 13. The contest is taking place at Centennial Bank Stadium in Jonesboro, Arkansas.

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Iowa State vs. Arkansas State Prediction

I predict Iowa State will win but Arkansas State will cover the 21-point spread. I also project the game will go Over 55.5 total points.

On paper, Iowa State is the better team with the better roster. And the Cyclones are 3-0 for a reason. But their two games against FBS opponents haven’t been smooth. They beat Kansas State and Iowa each by just three points.

And now they go on the road to take on Arkansas State, which should have a pretty solid offense this year. Red Wolves quarterback Jaylen Raynor is an experienced signal caller at this point, and I think he may prove to be tough to stop for Iowa State defensively. He’s completed 72% of his passes for 470 yards, four touchdowns, and two interceptions with 55 rushing yards.

Iowa State may end up winning, but considering this game is at home for Arkansas State, I think this matchup could also be decided by two touchdowns or less.

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