Stephen F. Austin has had several players selected in the NFL Draft.
Here are the past NFL Draft picks from SFA, with this list dating back to 1986.
SFA NFL Draft Picks
| Yr | Rd | Team | Player | Pos. |
| 2023 | 5 | KC | BJ Thompson | DE |
| 2018 | 4 | LAR | John Franklin-Myers | DE |
| 2011 | 7 | STL | Jabara Williams | LB |
| 2009 | 6 | TEN | Dominique Edison | WR |
| 2002 | 7 | BAL | Wes Pate | QB |
| 2001 | 5 | KC | Derrick Blaylock | RB |
| 1998 | 2 | SD | Mikhael Ricks | TE |
| 1998 | 3 | PHI | Jeremiah Trotter | LB |
| 1997 | 7 | TB | Anthony DeGrate | DT |
| 1996 | 7 | OAK | Joey Wylie | OL |
| 1995 | 2 | SD | Terrance Shaw | DB |
| 1990 | 4 | NYG | David Whitmore | DB |
| 1990 | 5 | PHO | Larry Centers | FB |
| 1990 | 10 | NE | Anthony Landry | RB |
| 1990 | 12 | TB | Todd Hammel | QB |
| 1986 | 6 | ATL | Floyd Dixon | WR |
