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Bowling Green vs. Louisville Prediction, Betting Odds & How To Watch

Colton Pool by Colton Pool
September 19, 2025
Bowling Green tight end Jyrin Johnson

AP Photo/Rick Osentoski

The Eddie George era at Bowling Green has started off on a good note.

The Falcons are 2-1 overall. They lost to Cincinnati by just two touchdowns, 34-20, but they’ve also won two games by double digits. They beat Lafayette 26-7 to start the season and also defeated Liberty, the preseason favorite to win Conference USA, 23-13 at home.

Will the Falcons have what it takes to compete in the MAC? We’ll have to see, because first they take on Louisville. Pulling off a Power Four upset on the road won’t be easy for BGSU. 


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Bowling Green vs. Louisville College Football Betting

Louisville is a -25.5 college football betting odds favorite against Bowling Green, with the Over/Under being 50.5. 

The moneyline for Bowling Green is +1500, while it’s -5000 for Louisville.


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Bowling Green vs. Louisville On TV

The matchup between Bowling Green and Louisville will be televised on the ACC Network. 

The game will kick off at noon ET on Saturday, Sept. 20. The contest is taking place at L&N Federal Credit Union Stadium in Louisville, Kentucky.

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Bowling Green vs. Louisville Prediction

I predict Louisville will win but Bowling Green will cover the 25.5-point spread. I also project the game will go Under 50.5 total points.

The Falcons have been a pleasant surprise, and I think they’ll continue to surprise some people here. 

BGSU has three players – Kaderris Roberts, Cameron Pettaway, and Chris McMillian – who have rushed for at least 100 yards already. They also have three players with at least 100 receiving yards – tight end Jyrin Johnson as well as wide receivers Finn Hogan and RJ Garcia II. With Drew Pyne, who has thrown for 529 yards and two touchdowns with no interceptions while completing 67% of his passes, at quarterback, the Falcons have plenty of playmakers they can turn to in order to sustain drives.

But I’m expecting both defenses to be at their best. BGSU is coming off a game where the Falcons limited Liberty to 13 points. Meanwhile, Louisville is averaging 15.5 points per game allowed and is coming off a bye.

That should give Louisville enough time to prepare for Bowling Green. That, and the fact the Cardinals are at home, is why I think Louisville will win. But I anticipate the Cardinals will have to win in a low-scoring battle.

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